First of all I am sorry if the question is out of topic here. Usually scientists doing computational research have to be satisfied with low impact publications. If collaboration with experimentalists results in high impact paper, their name is usually placed in the very of end of list of authors. Sometimes I only see some computational papers comparing genomes etc are published in Nature/Science.
On the contrary, many lucky crystallographers get published in higher impact journals. Often a mediocre experimental work gets published in a respectable journal. Is this the fate of a computational biologists of being second class scientist lacking confidence. On many occasions I have seen many experimentalists trying to undermine or not believing computational results.