For protein binding microarrays, how do you extract an 8mer sequence from your 35mer sequence?

Question

[anjali.gopal91]

I'm having trouble finding papers that describe how to convert a 35mer sequence to the 8mer motif representative of a TF binding sequence (given a dataset of 35mer motifs and the mean signal intensity). If anyone has additional resources for this, would you be able to refer me to it?

Thanks!

[natasha.sernova]

I found two papers for you to look at:

http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0020059

https://arxiv.org/ftp/arxiv/papers/1312/1312.4576.pdf

Hopefully they will help you.