Why does a SNP have to be in a peak to be a legit GWAS result.
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5.2 years ago
Tom ▴ 30

I notice that regularly, when authors are describing the relationship between a GWAS peak and a trait. Why does the SNP of interest have to be in a peak? Would a SNP that showed a significant association with a trait, but was not in a peak, be viewed as a spurious result? Thanks

GWAS peak association study SNP • 1.4k views
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What's a peak? If you can figure out what a running window of LOD is, then there's your answer.

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