Interpretation for regression coeffecient and T statistics from haplotype association in PLINK
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8.0 years ago
kumar.vinod81 ▴ 330

I have generated haplotype block of a chromosomal region and used it for hap association of quantitative trait in plink. I am ok with R2 and P-val but not with regression coeffecient and t statistics. I am getting two haplotype significantly associated but one with positive and one with negative Regression coeffecient (BETA) and T statistics. I dont know both are important or only one of them is important? Does anyone clarify this? thanks

LOCUS HAPLOTYPE NANAL BETA R2 STAT (T) P

H1 AAACACAGAGAGACAGGGCACCCA 141 -0.5084 0.2394 -6.614 7.46E-10

H1 GGGACACAGAGACAGAAAAGAAAG 141 0.5169 0.2139 6.149 7.77E-09

I dont know how to post table here, sorry.

haplotype association • 2.0k views
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