I have generated haplotype block of a chromosomal region and used it for hap association of quantitative trait in plink. I am ok with R2 and P-val but not with regression coeffecient and t statistics. I am getting two haplotype significantly associated but one with positive and one with negative Regression coeffecient (BETA) and T statistics. I dont know both are important or only one of them is important? Does anyone clarify this? thanks
LOCUS HAPLOTYPE NANAL BETA R2 STAT (T) P
H1 AAACACAGAGAGACAGGGCACCCA 141 -0.5084 0.2394 -6.614 7.46E-10
H1 GGGACACAGAGACAGAAAAGAAAG 141 0.5169 0.2139 6.149 7.77E-09
I dont know how to post table here, sorry.