Question: Immune cell specific data
1
gravatar for patvann
2.9 years ago by
patvann10
patvann10 wrote:

Hello! I am looking for the following:

  • B cell specific genes (around 100 or so)
  • Monocyte specific genes (around 100 or so)

I am trying to identify B cells and monocytes from single cell RNA sequencing data. I was able to identify T cells using the T cell specific genes named in this article (http://www.ncbi.nlm.nih.gov/pubmed/16339519). However I am unable to find a similar list for B cells and monocytes.

Any and all suggestions welcome. Thanks very much!

Best, Patrick

immune cells expression • 844 views
ADD COMMENTlink modified 2.9 years ago by natasha.sernova3.4k • written 2.9 years ago by patvann10
1
gravatar for natasha.sernova
2.9 years ago by
natasha.sernova3.4k
natasha.sernova3.4k wrote:

I'm not sure they have found about 100 genes for monocytes,

the authors studied different stages of monocyte development:

see the picture and paper below. In particular, "they reported the identification

and characterization of a progenitor of monocytes and

monocyte-derived macrophages. See Figure 8:

http://www.nature.com/ni/journal/v14/n8/fig_tab/ni.2638_F8.html

and the whole paper below:

http://sci-hub.io/10.1038/ni.2638 #

Concerning B-cells.

There were found a lot of B-cell specific genes, again, see the paper below:

http://bmcgenomics.biomedcentral.com/articles/10.1186/1471-2164-7-115

the authors have identified 427 "B-cell signature" genes.

Electronic supplementary material inside the paper does provide a list of genes.

ADD COMMENTlink modified 2.9 years ago • written 2.9 years ago by natasha.sernova3.4k
Please log in to add an answer.

Help
Access

Use of this site constitutes acceptance of our User Agreement and Privacy Policy.
Powered by Biostar version 2.3.0
Traffic: 2571 users visited in the last hour