Hello everyone, I want to assign COG categories to protein of my bacterial genomes. I have already done completed annotation part of the genome. But I'm finding some difficulties to work with COG, since there is proper way out of using COG. If someone of you have worked with COG before, please help me with this.
WebMGA can do that for you.
You just have to plot it as you wish.
get cog database from here and align it with your sequences by local blast program and find best hits based on identity, bit score or coverage yourself. Hits will have information about the cog id which can be linked to COG category for better display.