Hi all, I have a fundamental problem. Actually I just want the information of rearrangement between human and mouse genome. It seems UCSC provide this info. As the link http://hgdownload.cse.ucsc.edu/goldenpath/hg38/vsMm10/ shows: hg38.mm10.net.gz: "net" file that describes rearrangements between the species and the best Mouse match to any part of the Human genome. The net format is described in http://genome.ucsc.edu/goldenPath/help/net.html. I took a look in details about the description page, unfortunately, I still cannot really understand, problem like, what is the 'fill' line and 'gap' line mean respectively? what the relationship between two line with one space indent? and the more important is how I can get the rearrangement information? It would be great that these confusion can get answers. Thanks very much for your attention!!