Question: List of Indirectly binding transcription factors
gravatar for Kurui
3.8 years ago by
South Africa
Kurui0 wrote:

Does anyone know where I can find or have a curated list of human transcription factors known to bind indirectly or cooperatively?

ADD COMMENTlink modified 3.8 years ago by Denise - Open Targets5.1k • written 3.8 years ago by Kurui0
gravatar for Denise - Open Targets
3.8 years ago by
UK, Hinxton, EMBL-EBI
Denise - Open Targets5.1k wrote:

Check JASPAR and its publication. They seem to have some cases of multiple binding profiles for a given TF. You can view these CRMs in Ensembl too, as a result of the Ensembl Regulatory Build. Find out the TFs used to annotate a CTCF binding site (for example) on human chromosome 17 in the Region in detail view in the Ensembl browser.

ADD COMMENTlink written 3.8 years ago by Denise - Open Targets5.1k

Thank you for your answer. That is a very useful tool, and will be using it to explore further. I am actually looking for a list of TFs (e.g. TBP) that are known to bind indirectly to sequence via other TFs. This information can be obtained from various published papers, but I was just wondering if there is a curated list available.

ADD REPLYlink written 3.8 years ago by Kurui0
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