Question: Ranking genes from cluster map
0
gravatar for Govardhan Anande
3.1 years ago by
Australia
Govardhan Anande130 wrote:

How should I rank the top contributing genes to cluster.

For example : If I use 100 genes from 5 samples to perform clustering, then how can I get the top 20 contributing genes to that cluster.

Thank you in advance.

ADD COMMENTlink modified 3.1 years ago by Jean-Karim Heriche21k • written 3.1 years ago by Govardhan Anande130
0
gravatar for Carlo Yague
3.1 years ago by
Carlo Yague4.7k
Canada
Carlo Yague4.7k wrote:

If the clustering is build in order to highlight differences between samples, you could define the top 20 genes as the genes with the highest coefficient of variation across samples.

ADD COMMENTlink written 3.1 years ago by Carlo Yague4.7k
0
gravatar for Jean-Karim Heriche
3.1 years ago by
EMBL Heidelberg, Germany
Jean-Karim Heriche21k wrote:

A general and widely used indicator is the silhouette.

ADD COMMENTlink written 3.1 years ago by Jean-Karim Heriche21k
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