Ranking genes from cluster map
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5.2 years ago

How should I rank the top contributing genes to cluster.

For example : If I use 100 genes from 5 samples to perform clustering, then how can I get the top 20 contributing genes to that cluster.

Thank you in advance.

RNA-Seq sequencing gene clustering ranking • 1.1k views
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Entering edit mode
5.2 years ago

If the clustering is build in order to highlight differences between samples, you could define the top 20 genes as the genes with the highest coefficient of variation across samples.

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5.2 years ago

A general and widely used indicator is the silhouette.

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