Please, I need some clarification about using MACS in the Galaxy plataform. I have BAM files from my chip-seq experiment and the peak calling was performed with tag size 50. I have runned again the BAM files in MACS in the galaxy platform but using a tag size 36. The late gave me results that fit better to what I expect (less peaks in the control vs more peaks in the treatment). Is it ok to do that? I am very very raw in bioinformatics so I apolgize if this is a very basic question. Do I have to look the average of the tags resulting from the chip experiment?