I've downloaded all pairs of orthologs (oma-pairs.txt file) from the OMA website and I wonder whether it is possible to find, for different taxonomic ranges, the HOGs starting from this file, without running the oma standalone program again for all organisms present in the oma-pairs.txt file.
For instance, I would like to find all HOGs in metazoa and then all HOGs in mammals. Would I need to start from scratch and create a DB folder with all metazoa genomes and another DB folder with all mammal genomes, and run oma for every one?
In other words: is it possible to run GETHOGs independently from the OMA standalone program? If yes, which kind of input should I use?
Thanks a lot in advance