Question: Binding Affinity prediction
gravatar for ashamscsoft
2.1 years ago by
ashamscsoft10 wrote:

i have a doubt in binding affinity prediction. My doubt is im getting positive value for affinity. The formula i used to calculate is kd=[l][p]/[lp], where l is ligand molar concentration and p is protein molar concentration and [lp] is complex molar concentration. I calculated molar concentration by keeping the molecular weight of ligand, protein and complex respectively. The value atlast i get is kd=6.69. If i take log for this im gettin in 0.83. But the affinity value should be in negative only right? Is this correct or not? Kindly anyone help to sort out this

ADD COMMENTlink written 2.1 years ago by ashamscsoft10
Please log in to add an answer.


Use of this site constitutes acceptance of our User Agreement and Privacy Policy.
Powered by Biostar version 2.3.0
Traffic: 1492 users visited in the last hour