How to integrate PWM data into variant filtering

Question

[nina]

Hi,

Does anyone have any idea to integrate position weight matrix data into variant filtering (prioritization)?

[natasha.sernova]

See these papers:

http://nar.oxfordjournals.org/content/early/2014/11/21/nar.gku1206.full

https://www.semel.ucla.edu/research/variant-filtering-ranking-pipeline

https://genomebiology.biomedcentral.com/articles/10.1186/s13059-014-0480-5

These three consider different problems.

[nina]

Thank you for the link! It will help me a lot.