Question: Conservation Score Of Amino Acid Positions (2017)
gravatar for bhffs01
3.0 years ago by
bhffs0110 wrote:

I am looking to calculate per position conservation scores for multiple alignments of amino acids. I have fasta files for each exon in hg19 aligned to 46 primates, mammals, and vertebrates (the 46 way ucsc alignment).

I've seen this question be asked a few times but quite a long time ago (> 4~5 years.) I'm wondering if there are any newer tools to solve this problem. There is plenty for nucleotide positions but I need AA specifically.

ADD COMMENTlink written 3.0 years ago by bhffs0110
  1. I'll always prefer an old tool which is still maintained over a new one.
  2. You can look for papers citing old tools to see which new tools are out there.
ADD REPLYlink written 3.0 years ago by Asaf7.2k
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