Question: Which genes or proteins to compare in a phylogenetic tree?
gravatar for crawforc3
11 months ago by
crawforc330 wrote:

I am a student and I have a fun problem: My friend doesn't like cats and thinks raccoon's are "way cooler." I want to build a phylogenetic tree and show him that we're more closely related to cats and therefore cats are cooler.

However, my school assignments always told me which gene or protein to use for analyses.

So how do I decide which gene/prot to compare without looking back at old assignments?

I'll be looking at house pets so I know I need something that cats, dogs, lizards, gold fish, and snakes have in common.

What should be my next steps?

evolution gene genome • 292 views
ADD COMMENTlink modified 11 months ago by Jean-Karim Heriche14k • written 11 months ago by crawforc330
gravatar for Jean-Karim Heriche
11 months ago by
EMBL Heidelberg, Germany
Jean-Karim Heriche14k wrote:

Phylogenies using a single gene are not reliable. For this kind of comparison, you should probably use fast evolving genes such as mitochondrial genes. Check the literature, people have most likely already worked out which genes to use and how.

ADD COMMENTlink written 11 months ago by Jean-Karim Heriche14k

Why faster evolving genes? Would that make a more apparent differentiation?

ADD REPLYlink written 11 months ago by crawforc330

Because you're interested in species which diverged relatively recently i.e. their most recent common ancestors are not old so faster evolving sequences will contain more information.

ADD REPLYlink written 11 months ago by Jean-Karim Heriche14k
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