Trait specific SNP prioritization
0
0
Entering edit mode
5.1 years ago
LNA ▴ 30

Dear all, I am doing a GWAS for which I have only few samples available. According to the p-values I calculated using PLINK I don't have many significant signals. I would like to further investigate the SNPs with p-values in the "medium range" and now I am looking for a suitable prioritization tool, which can rank my SNPs according to the affiliation with keywords that are related to my studied trait (which could simply be a tissue type or more specifically proteins that are known to be important for the phenotype). A came across GeneSniffer, which seemed to use a list of keywords and a list of genes/SNPs to perform a ranking. Anyway, seemed to be doing what I would like to do, but it is not available anymore (or did I miss anything?).

Do you have any suggestions which tool would be best for this situation?

Thank you for your help!

SNP gwas enrichment prioritization • 1.2k views
ADD COMMENT

Login before adding your answer.

Traffic: 2317 users visited in the last hour
Help About
FAQ
Access RSS
API
Stats

Use of this site constitutes acceptance of our User Agreement and Privacy Policy.

Powered by the version 2.3.6