Dear all, I did an orthology analysis for four species and annotated the orthogroups which are unique for one of the species or species groups. Now I want to compare the found GO terms to each other if there are any statistical differences between the species. Furthermore, I want to compare the results between two groups of species (two species are sexual and the other two are asexual). The data looks like that:
Go term Spec1 Spec2 Spec3 Spec4 Spec1&2 Spec3&4 database GO:0000003 23 0 4 5 1003 508 26755 GO:0000228 2 0 0 5 190 96 7349 GO:0000278 14 42 9 0 371 92 10200 Total 39 42 13 10 1564 696 136800
The numbers represent the counts of the found GO term for each species or species group, respectively. The last column is the number from the reference database. Which test should i use to detect the GO terms with a significant difference between the species sets?
I really appreciate any help you can provide.