we still have a few spots available for the Workshop "Genomic Data Visualization and Interpretation".
11th-15th September, Berlin (Germany)
Instructors: Dr Obi Griffith and Dr Malachi Griffith (Washington University School of Medicine)
Topic: Advanced R and bioinformatics applications for visualization and interpretation of genomic data.
The advent of rapid and relatively cheap massively parallel sequencing has dramatically increased the availability of genome, transcriptome, and epigenome profiling. Analysis workflows and published best practices are also now available to process raw sequence data into alignments, variant calls, expression estimates, etc., in relatively standardized file formats. Interpretation and visualization of these data, often consisting of thousands to billions of data points, and extracting biological meaning remains a serious challenge. In this workshop we will explore a number of best-in-class visualization tools, and provide working examples that demonstrate important principles of ‘omic interpretation strategies.
The workshop will be delivered over the course of five days. Each day will include an introductory lecture with class discussion of key concepts. The remainder of each day will consist of practical hands-on sessions. These sessions will involve a combination of both mirroring exercises with the instructor to demonstrate a skill as well as applying these skills on your own to complete complete individual exercises. After and during each exercise, interpretation of results will be discussed as a group. Computing will be done using a combination of tools installed on the attendees laptop computer and web resources accessed via web browser.
Who should attend
This workshop is aimed at researchers and technical workers who are analyzing some kind of omic data (e.g. WGS, exome, RNA-seq, variant files, etc.). Examples demonstrated in this course will involve primarily human genome/transcriptome data but many of the concepts learned will be applicable to model organisms, metagenomics, simulated data, etc.
Attendees should have a background in biology and a basic knowledge of R. We will dedicate one session to a brief R/linux primer. Attendees should have also some familiarity with genomic data. The course will teach relatively advanced usage of R (especially ggplot2 and Bioconductor packages). Attendees should have a working installation of R and RStudio on their laptop.
Attendees will learn to visualize and interpret results from real human genome data sets generated at the McDonnell Genome Institute at Washington University School of Medicine. These data will be analyzed to determine previously known as well as potentially novel interpretations. Since the example data are not simulated or arbitrarily filtered, interpretation and visualization will be performed in the context of representative levels of sequence error, and other sources of technical and biological noise.
For for more information about the programme, please visit our website: https://www.physalia-courses.org/courses-workshops/course14/
Application deadline is the 10th of August 2017.