Pfam/Hmmer redundant annotations
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3.4 years ago

Hi all,

I am annotating some protein sequences with Pfam domains using Hmmer3, and I have noticed that if there are multiple domains with a closely related, very similar, profile, Hmmer will just return a hit for all of them, instead of going for the most specific one. Does anyone have a good way to fix this?

Thanks

pfam hmmer annotations • 985 views
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