I want to pose everyone a question, i know filtering options depend on the strictness threshold anyone would like, depending on his/her research question,
On a vcf, the quality column, is expressed in phred parameters? ... if not so, which parameters? and, the actual question..
what filtering quality would be the most appropiate to set as lowest in your analysis?, i am interested on the evolution of a bone growth-related gene in humans.
thanks in advance for any interaction