How to do GO annotation with non-model animal
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3.3 years ago
jiang_lan • 0

I don't know choose which tool to annotate with non-model animal, I tried the R package "AnnotationHub", however, the GO result is empty with NA, please help me! Thanks a lot.

rna-seq • 1.1k views
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3.3 years ago

The way to do this is to transfer annotations by orthology, i.e. use annotations from orthologs in well-annotated species.

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Thanks a lot. Could I run the GO annotation by myself?

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What do you mean by 'run the GO annotation' ? You identify orthologs of your gene G in species X then take the GO terms associated with the orthologs of G in X and assign them to G. You could use more than one species to transfer annnotations in this way.

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23 months ago

Hello, You can easily annotate GO functions for your own proteomes online using OMA: https://omabrowser.org/oma/functions/

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