Alignment of protein domains with MDAT: Any suggestions?
0
0
Entering edit mode
6.3 years ago

Hi guys, I was wondering to know if some of you have used MDAT program (http://www.bornberglab.org/pages/mdat), this is an aligner for protein domains. But it seems to be a little bit old and there are no good descriptions of the way to use it. The --help flag gave me:

[faf43525@52563es1 MDAT]$ /usr/local/bin/mdat --help
MDA v1.0  Copyright (C) 2013,2014  Carsten Kemena
This program comes with ABSOLUTELY NO WARRANTY;

Allowed options are displayed below.:

General options:
 -h [ --help ]                  Produces this help message
 -s [ --sequence ] arg          Sequence file
 -d [ --domain_f ] arg          Domain file
 -o [ --msa_out ] arg           File to write the MSA to.
 -a [ --mda_out ] arg           File to write the MDA to.
 -f [ --format ] arg (=fasta)   Output format for the MSA
 -t [ --threads ] arg (=1)      Number of threads to use

Some ideas to use it? do not know what is i.e Domain file. Because the flag --domain_f is mandatory. Thanks a lot.

Protein domains Domains alignment • 1.1k views
ADD COMMENT
1
Entering edit mode

Take a look at the README.md file included in the distribution. It says this:

Certain data is need by MDAT. For it to be found automatically you need to copy the content of the folder data into a (hidden) folder in your home named ".mdat". Alternatively you can give the domain math probably matrix manually using the '--dmpm_f' option.

Even though there is a doc folder in the distro it seems to mainly contain information about software and not how to use it.

ADD REPLY

Login before adding your answer.

Traffic: 1605 users visited in the last hour
Help About
FAQ
Access RSS
API
Stats

Use of this site constitutes acceptance of our User Agreement and Privacy Policy.

Powered by the version 2.3.6