Hello! What's the biggest differences between bisulfite sequencing and regular genomic sequencing?
Is it higher depth for BS-sequencing is nessary to identify methylation signature than other kinds of genotyping?
For the bisulfite treatment, I it will reduce the DNA sequence complexity. Apart from this, are there some other trick points in this library preparation(steps/techniques) than other regular genomic libraries?
Personally, short clear answers in one or two sentences are preferred. And bomb me with the links. Wish you all guys have a nice weekend.