The Biomedical Data Science Group (led by Dr. Enrico Glaab) and the Developmental and Cellular Biology Group (led by Prof. Jens Schwamborn) at the Luxembourg Centre for Systems Biomedicine utilize human stem cells for modeling of neurodegenerative disease and for the development of novel drugs to experimentally treat these diseases. Projects are at the interface of systems biology and bio-medical research. In particular we aim on gaining new insights into the complex processes that regulate neuro-degenerative as well as -regenerative processes.
In this project for a research intern or Master student we will use human Parkinson's disease patient specific induced pluripotent stem cells (iPSCs) to generate complex three-dimensional models of the disease. In these models, phenotypes shall be identified and computationally predicted drug candidates tested. The project combines elements of stem cell research, neurobiology, preclinical drug development and high-content imaging.
Successful applicants should have a strong interest in cell biology and neurobiology, especially experience in stem cell biology and/or high-content imaging would be a plus. We are looking for highly motivated candidates who share our passion for research, are interested in acquiring new skills and wish to be part of an international team.
Application:
Applications (in English) should contain the following documents:
- A detailed curriculum vitae
- Cover letter
- Name and addresses of referees
Please send your applications and possible questions with the subject line "Research intern or Master student project on human stem cell based phenotyping and drug development " to:
Jens Schwamborn (jens.schwamborn@uni.lu) or Enrico Glaab (enrico.glaab@uni.lu)
