I am blasting several assembled contigs from IDBA-UD with lengths between 13,000 and 250bp. BLAST+ seems to be taking a very long time to achieve this. I am using a local
nt database and the job should have plenty of memory (25Gb). If I take this same file and use the web based BLAST portal it takes under 10 minutes. What explains the extremely slow local speeds? Is there anything I am not configuring properly?
This is being run through SLURM.