Question: (Closed) why a stop-loss is pathogenic
0
gravatar for Dayna
10 months ago by
Dayna20
Dayna20 wrote:

Hi every one

Could anyone explain why a stop-loss is pathogenic? Like why causing an elongated protein is pathogenic?

snp • 438 views
ADD COMMENTlink written 10 months ago by Dayna20

because some extra amino acids could break the conformation of the protein -> active domain is broken.

closing as it's not related to bioinformatics.

ADD REPLYlink modified 10 months ago • written 10 months ago by Pierre Lindenbaum118k

Hello Dayna!

We believe that this post does not fit the main topic of this site.

I'm closing this question as it's not related to bioinformatics.

For this reason we have closed your question. This allows us to keep the site focused on the topics that the community can help with.

If you disagree please tell us why in a reply below, we'll be happy to talk about it.

Cheers!

ADD REPLYlink written 10 months ago by Pierre Lindenbaum118k

Why a stoploss mutation is not related to bioinformatics? Shouldnot we understand the type of mutations we try to discover from data?

ADD REPLYlink written 10 months ago by Dayna20
2

Because it's a basic concept of molecular biology, you would expect to find in good text books on the topic. As a rule of thumb, we do not attempt to explain basic concepts of molecular biology on this site that have better explanation elsewhere.

ADD REPLYlink modified 10 months ago • written 10 months ago by Michael Dondrup45k
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