Question: Does sciClone work on mouse exome data?
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gravatar for sm.hashemin
12 months ago by
sm.hashemin80
sm.hashemin80 wrote:

Dear people, could I run the sciclone to find subclones from mouse WES data? Best Mo

sciclone clonevol • 345 views
ADD COMMENTlink modified 6 weeks ago by Biostar ♦♦ 20 • written 12 months ago by sm.hashemin80

It is not a totally absurd idea, take a look https://www.sciencedirect.com/science/article/pii/S2211124717305764 http://cancerimmunolres.aacrjournals.org/content/5/1/29.long

ADD REPLYlink written 12 months ago by sm.hashemin80
1
gravatar for Chris Miller
6 months ago by
Chris Miller21k
Washington University in St. Louis, MO
Chris Miller21k wrote:

I don't see why that wouldn't work, as long as there are enough somatic variants to track from the tumors. (Cluster confidence increases with number of variants and the depth of sequencing).

ADD COMMENTlink written 6 months ago by Chris Miller21k
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