Question: Does sciClone work on mouse exome data?
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gravatar for sm.hashemin
7 months ago by
sm.hashemin60
sm.hashemin60 wrote:

Dear people, could I run the sciclone to find subclones from mouse WES data? Best Mo

sciclone clonevol • 219 views
ADD COMMENTlink modified 5 weeks ago by Chris Miller20k • written 7 months ago by sm.hashemin60

It is not a totally absurd idea, take a look https://www.sciencedirect.com/science/article/pii/S2211124717305764 http://cancerimmunolres.aacrjournals.org/content/5/1/29.long

ADD REPLYlink written 7 months ago by sm.hashemin60
1
gravatar for Chris Miller
5 weeks ago by
Chris Miller20k
Washington University in St. Louis, MO
Chris Miller20k wrote:

I don't see why that wouldn't work, as long as there are enough somatic variants to track from the tumors. (Cluster confidence increases with number of variants and the depth of sequencing).

ADD COMMENTlink written 5 weeks ago by Chris Miller20k
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