Conversion from SNP physical map to genetic distance

Question

[paolo002]

Hi all,

I have converted a vcf file to map and ped file by plink. Here is an example of the map file format:

SNP.      genetic map           physical map
rs1234.        0                     100
rs5678.        0                     200
rs9123.        0                     300
rs456          0                     400 
rs...          0                     500

I would like to convert the physical map to genetic distance (genetic map) to replace all the zeros. I there any efficient solution to this?

Best

[zx8754]

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