I'm new to the field of metagenomics and I have been reading research work done on binning in metagenomics.
I have been reading this paper where the authors discuss about different metagenome binning approaches. The last approach is Differential abundance (DA). They explain the starting point of this method as differential coverage patterns across multiple samples where population changed in abundance over time. Can someone kindly explain to me what is meant by differential abundance? Is it the abundance of genomes in different samples?
Sorry if this is a naive question. I would really appreciate an explanation. :) Thank you!