Drug target discovery with single cell RNA-seq
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5.3 years ago
chipolino ▴ 150

Hi everyone!

Suppose, I have single cell RNA-seq data with two time points: cells at zero time point that are not treated by some drug, cells after the drug treatment. My goal is to identify a mechanism of action of this drug (its targets). Is there any good way of how I can do it? I was thinking about gene regulatory network analysis but I am not sure, how it can help me find drug targets. Are there any good tools for this? This is my first experience of working with scRNA-seq.

Thank you for any suggestions!

scRNA-seq drug target • 1.4k views
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