Dear all great helpers,
Practically, I'm a biologist and I've just start learning MeDIP-seq analysis. Due to my lack of experience in both concept and data pre-procession, I'm wondering if the performance of GC-bias correction is valid with such data. As far as I understand MeDIP aim to enrich methylated DNAs, CpG regions were highly expected. However, I'm wondering if both low and high CpG regions are supposed to be included?
I must apologize you in advance if I've totally mistaken anything in my question.
Best regards Kaj