Question: Sample size calculation for GWAS (fixed number of controls)
1
gravatar for khn
10 days ago by
khn100
khn100 wrote:

Hello

I usually calculate sample sizes for GWAS using QUANTO. This time, the number of controls is already decided to 800, so QUANTO is not suitable to calculate the number of cases. In this case, which software would be better for sample size calculation?

Thank you in advance!

snp • 95 views
ADD COMMENTlink modified 9 days ago by Kevin Blighe35k • written 10 days ago by khn100
1
gravatar for Kevin Blighe
9 days ago by
Kevin Blighe35k
Republic of Ireland
Kevin Blighe35k wrote:

Probably the best option is CaTS: CaTS -- Power Calculator for Two Stage Association Studies

Another popular one but not quite what you want (adding for reference) is PS: Power and Sample Size Calculation

Kevin

ADD COMMENTlink written 9 days ago by Kevin Blighe35k
1

Thank you so much for your reply! 1. CaTS -> I think only power can be calculated, not sample sizes? 2. PS -> This seems to be perfect for my analysis.

Thank you!!

ADD REPLYlink modified 8 days ago • written 8 days ago by khn100
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