Question: Sample size calculation for GWAS (fixed number of controls)
gravatar for khn
3 months ago by
khn100 wrote:


I usually calculate sample sizes for GWAS using QUANTO. This time, the number of controls is already decided to 800, so QUANTO is not suitable to calculate the number of cases. In this case, which software would be better for sample size calculation?

Thank you in advance!

snp • 280 views
ADD COMMENTlink modified 3 months ago by Kevin Blighe41k • written 3 months ago by khn100
gravatar for Kevin Blighe
3 months ago by
Kevin Blighe41k
London, England
Kevin Blighe41k wrote:

Probably the best option is CaTS: CaTS -- Power Calculator for Two Stage Association Studies

Another popular one but not quite what you want (adding for reference) is PS: Power and Sample Size Calculation


ADD COMMENTlink written 3 months ago by Kevin Blighe41k

Thank you so much for your reply! 1. CaTS -> I think only power can be calculated, not sample sizes? 2. PS -> This seems to be perfect for my analysis.

Thank you!!

ADD REPLYlink modified 3 months ago • written 3 months ago by khn100
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