Unknown gene names in Clariom D human Gene chip annotation files?
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5.2 years ago
mgab ▴ 60

Dear All, I am using Clariom D gene chip (Human). I have performed Differential gene expression (DEG) using the Clariom D Human microarray and used the annotation file (transcript) from the link below

https://www.thermofisher.com/sa/en/home/life-science/microarray-analysis/microarray-data-analysis/genechip-array-annotation-files.html

In the list of DEG, there are many gene names (coding) in lower case letters that I am unable to identify, such as shasmar, tusweyb, nugo etc. Should I use them in analysis? Is there a file which has both probeset ID and its corresponding entrez gene ID (Gene symbol). Thank you

Clariom D • 2.1k views
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Thanks Genomax. Can one use such gene names in differentially expressed gene analysis?

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If the gene no longer exists in current genome build then I would be hesitant to use them. You could leave them in (if they don't overlap with known current genes) but then not use them for actual downstream analysis.

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Thanks Genomax. Much appreciated.

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