Question: Appear negative value while caculating Input-subtract signal for ChIP-Seq
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gravatar for biofandd
10 months ago by
biofandd0
biofandd0 wrote:

For a region, the signal in treat sample is 0, but have signal in Input-background. Therefore, It will appear negative value while caculating Input-subtract signal. How to do with this situation?

chip-seq • 199 views
ADD COMMENTlink written 10 months ago by biofandd0

I use to set those regions to 0 in my ChipSeq analysis, as you can not have less than nothing

ADD REPLYlink written 10 months ago by Bastien Hervé4.5k
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