Question: How to compile a list of non-cancerous mutations
gravatar for banerjeeshayantan
21 months ago by
banerjeeshayantan190 wrote:

I am trying to perform a one-class classification of driver vs non-driver mutations. I have a list of experimentally validated driver mutations from a pancancer study. But is it possible to retrieve a list of non-cancerous mutations as well? Since the number of non-cancerous mutations far exceeds the number drivers, I would train a one-class SVM on the list of non-cancer mutations and predict the outliers as drivers. But before that, I need a list of such high confidence non-cancer mutations. Is there a way to compile a list from different databases?

cancer next-gen sequencing • 366 views
ADD COMMENTlink modified 21 months ago • written 21 months ago by banerjeeshayantan190
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