PhD position in translational clinical implementation of metagenomics
A PhD position is available for 3 years in the Research Core Unit Genomics at Hannover Medical School in Hannover, Germany starting in October 2019 (or later). Salary will be according to the domestic TV-L tarif (0.65 E13).
The applicant will be working in the modern Pediatric Research Center. Modern cluster computational infrastructure, MGI-seq, NextSeq, Miseq, Pacbio and MinION sequencers are established at present.
Key aspect of the applicant's work will be the evaluation and analysis of next-generation sequencing data in various research projects conducted on site, including projects from the German Lung Centre and the Lower Saxony Big Data OMICS initiative as well the Cluster of Excellence RESIST.
The main project will be focused on the project “Airway microbial metagenome diagnostics for patient care: From bedside to bench to bedside in two working days”. The student will be in charge of sample collection, innovative logistics, DNA extraction prior to sequencing and quality control and taxonomic classification of reads after sequencing. The student will perform the rapid bioinformatic analysis of single specimens and the joint analysis of samples from large cohorts. The third year of the PhD will include application of machine learning techniques learned from experts at the Leibniz University. Other tasks include a diverse range of sequencing analysis projects from epigenomics to genome and single cell analysis.
We offer a modern work environment in a multidisciplinary team, composed of bioinformaticians, molecular biologists, biochemists, and medical scientists. Hannover Medical School is an established institution with proven ground-breaking research and several Excellence Clusters and is a leader in acquiring grant funding. Hannover, the state capital of Lower Saxony, has a population of 550,000 and lies within easy reach of excellent summer and winter recreational areas in the Harz mountains, Steinhuder Meer and the North and Baltic seas. The city hosts three University campuses and offers a good standard of living.
- NGS data analysis
- Ability to proactively interact with patients and doctors
- Wet lab sample preparation
- Wet lab experience
- Knowledge of metagenomics (not 16S) and microbial genetics
- Very good spoken and written English
- Ability to work in an interdisciplinary team
- Experience with next-generation sequencing analysis
- Linux or programming experience
Hannover Medical School strives to increase the number of women in scientific positions. Applications from women are thus particularly welcome. Disabled candidates will be preferred given equal skills and abilities. Please submit applications with two references as a single PDF by email only to Dr. Lutz Wiehlmann, wiehlmann(dot) lutz |at| mh-hannover (dot) de before 31.8.2019.