Question: Homology in EMBL Biomart
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gravatar for The Last Word
11 months ago by
The Last Word190
India
The Last Word190 wrote:

Hi,

I am wondering what software determines homologous genes in Ensembl. Biomart,. Is it just a normal BLAST? I also have a second question. A paper which was published 7 years ago was able to find homologous genes for a set of 300 genes. However, I was able to find homologous genes for 215 genes from the same set? I do understand that biological information contained in the different databases keep changing, however, I was not expecting information to disappear for 80+ genes. Thank you for any information that is offered

homology biomart • 300 views
ADD COMMENTlink modified 11 months ago by Ben_Ensembl1.5k • written 11 months ago by The Last Word190
1
gravatar for Ben_Ensembl
11 months ago by
Ben_Ensembl1.5k
EMBL-EBI
Ben_Ensembl1.5k wrote:

Hi The Last Word,

In Ensembl, homologues are inferred from the gene trees we produce as part of our comparative genomics analyses: http://www.ensembl.org/info/genome/compara/homology_method.html

We do not use known/curated lists of homologous genes in our predictions.

Best wishes

Ben Ensembl Helpdesk

ADD COMMENTlink written 11 months ago by Ben_Ensembl1.5k
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