A pre-defined gap penalty is usually used during DNA sequence alignment. However, In RNA-Seq the intron gap can be really long. I think usual gap penalty (for example affine) does not apply in such situation. So How do splice-aware aligners treat such gaps during matrix scoring?
Question: How splice-aware aligner (RNA-Seq) deal with long gap (intron) penalty
8 months ago by
CY • 470
CY • 470 wrote:
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