Question: Variant Annotation and prioritization
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gravatar for mandar.bedse
5 days ago by
mandar.bedse0 wrote:

I have data of Whole Exome Data of Human with Pancreatic Cancer patient: I would like you to, 1. Annotate the variants 2. Prioritize variants on various parameters of importance
3. Extract Genotype information for the Non-Synonymous Variants.

Could anybody suggest me the tools to achieve this objective?

sequence next-gen • 68 views
ADD COMMENTlink modified 5 days ago by Vitis2.3k • written 5 days ago by mandar.bedse0
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gravatar for Vitis
5 days ago by
Vitis2.3k
New York
Vitis2.3k wrote:

The annotation tools snpEff would be a good start. You may also look at PyVCF to extract genotypes from VCF files.

http://snpeff.sourceforge.net

https://pyvcf.readthedocs.io/en/latest/

ADD COMMENTlink written 5 days ago by Vitis2.3k
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