Does variant enrichment analysis make sense?
0
0
Entering edit mode
5.0 years ago
CY ▴ 750

Gene set expression analysis have been wide used in find significantly dis-regulated pathways in given population. We also found some similar enrichment analysis tools using somatic variants. Does this make biological sense. Besides, somatic variants are sparse and I think it would not be able to provide enough statistical power for enrichment analysis, right?

enrichment analysis somatic variant expression • 1.0k views
ADD COMMENT
0
Entering edit mode

We also found some similar enrichment analysis tools using somatic variants.

Which tools?

ADD REPLY
0
Entering edit mode

One is COBAS (http://kobas.cbi.pku.edu.cn/). I am not sure if there are others. But this one seems to be frequently used although I don't think this type of analysis make sense.

ADD REPLY

Login before adding your answer.

Traffic: 1012 users visited in the last hour
Help About
FAQ
Access RSS
API
Stats

Use of this site constitutes acceptance of our User Agreement and Privacy Policy.

Powered by the version 2.3.6