How to calculate rate of synonymous substitution at 4 fold and 2 fold degenerate sites?
Entering edit mode
2.5 years ago

Hello experts,

I was reading

'Bierne, Nicolas, and Adam Eyre-Walker. "The problem of counting sites in the estimation of the synonymous and nonsynonymous substitution rates: implications for the correlation between the synonymous substitution rate and codon usage bias." Genetics 165.3 (2003): 1587-1597.'

However, I want to know how can I calculate the rate of synonymous substitution at four-fold (DTs4) , rate synonymous substitution at two-fold degenerate sites (dBs2) and the total number of synonymous substitutions per codon (DcBs) . How can I calculate it is there any software available for the same. HELP

Thanks in advance

gene substitution PAML • 875 views

Login before adding your answer.

Traffic: 1761 users visited in the last hour
Help About
Access RSS

Use of this site constitutes acceptance of our User Agreement and Privacy Policy.

Powered by the version 2.3.6