Entering edit mode
4.2 years ago
katie.connor
•
0
Hi Everyone,
I was hoping you could help. I have a list of differentially expressed miRs clusters in mouse. I want to apply this expression date to lists of differentially expressed human miR datasets. I prefer to use an R workflow.
To do this ideally I think I would need to join the names/IDs/sequences of the human data to the mouse. At the moment, this only partially works. e.g. miR-21 human would not match to miR-21a in mouse.
Is there a way you would recommend doing this? Or is the conservation too poor to recommend this approach at all?
Thank you for your help!
This is an older thread but the resource mentions by @Alastair should be easy to check: How Can I Find The Conserved Microrna Genes Between Human And Mouse
Thanks very much for this - I've had a go with @Alastair using Biomart on the ENSEMBL Website. Using this I generated about 250 murine microRNAs from the 2000 or so human miRs.
I was wondering if there was another approach anyone can recommend? Very grateful for your help!
K