Question: Conversion of human miRBase Accession/Name/Sequence to murine
gravatar for katie.connor
12 months ago by
katie.connor0 wrote:

Hi Everyone,

I was hoping you could help. I have a list of differentially expressed miRs clusters in mouse. I want to apply this expression date to lists of differentially expressed human miR datasets. I prefer to use an R workflow.

To do this ideally I think I would need to join the names/IDs/sequences of the human data to the mouse. At the moment, this only partially works. e.g. miR-21 human would not match to miR-21a in mouse.

Is there a way you would recommend doing this? Or is the conservation too poor to recommend this approach at all?

Thank you for your help!

microrna mirbase • 199 views
ADD COMMENTlink modified 11 months ago • written 12 months ago by katie.connor0

This is an older thread but the resource mentions by @Alastair should be easy to check: How Can I Find The Conserved Microrna Genes Between Human And Mouse

ADD REPLYlink written 12 months ago by GenoMax94k

Thanks very much for this - I've had a go with @Alastair using Biomart on the ENSEMBL Website. Using this I generated about 250 murine microRNAs from the 2000 or so human miRs.

I was wondering if there was another approach anyone can recommend? Very grateful for your help!


ADD REPLYlink written 11 months ago by katie.connor0
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