Hello, Regarding using the Hmmer (3.1b1) my requirement is to search amino acid sequences of predicted protein products against an HMM database prokaryotic viral orthologous groups. Which I know can be done using hmmscan.
The user guide says hmmpress has to be performed to prepare a database to run hmmscan on the the test file. But the vog file from the website ( http://dmk-brain.ecn.uiowa.edu/pVOGs/downloads.html ) downloads a tar.gz file and hmmpress asks for a Hmmer3 file. I have no idea about this step and getting confused over it.
Can anyone help me in this reagrds,Please?