Question: RNA-seq find marker genes
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gravatar for massimo.larosa
10 days ago by
massimo.larosa0 wrote:

Hi all, How can I extract marker genes from an RNA-seq expression profile matrix? I tried MGFR algorithm (https://bioconductor.org/packages/release/bioc/html/MGFR.html) but unfortunately the resulting marker list does not contain the marker gene names even if the algorithm works. Is there any other way to compute those biomarker?

Best

Massimo

ADD COMMENTlink written 10 days ago by massimo.larosa0

Ciao, what is the aim of your work?; how would you define a 'marker'? There are countless / many ways that one can find marker genes. It could be via:

  • differential expression
  • regression
  • classification algorithms
  • Z-scores
  • et cetera
ADD REPLYlink written 9 days ago by Kevin Blighe54k
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