Maybe is a silly question but I found no clear information about. I generated the 3D models of a COL4A5 protein with a missense mutation c.2546G>A p.(Gly849Glu) through Phyre2 (here link to my results) and the protein inserted FASTA is ~1690 residues. The generated primary model is only from residue 1464 to 1691. I checked and the model in the COL4A5 UniProt page is identical and relative to this little portion.
My question is: why all the rest of the AA sequence is not showed in the model? If I try to open the relative model from Phyre2 results that is just a long sequence without structure...is there any theoretical reason for that that I am missing? How can I visualize the impact of my mutation on the protein if it does not fall in this little window?
Thank so much in advance