hmmer from multiple alignment with t-coffee (proteins sequences)
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18 months ago
eridanus ▴ 30

hello!please i would like your help! i need to do a project about my master. i have 11 proteins sequences in a file (multiple alignment with TCOFFEE) and i need to build a pHMM and to search against Swissprot, using hmm search. My question is when i use hmm search with multiple alignment data, does it automatically translate it to a pHMM?how does it work? should i use the hmmerbuild first in order to create the pHMM? (i have windows and i cannot installe it so easily) please help me :)

alignment sequence phmm hmmer • 341 views

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