I am using abodybuilder for large-scale antibody modeling of the ncov-2019,about a few hundred antibody sequences, but I have some problems:
- Is there any way to modeling antibody with large-scale ?
- I don’t know if I need to use gromacs for molecular dynamics simulation after modeling with abodybuilder?
- I have a problem when using FREAD alone, I don’t know where to download the loop database?
- I am a beginner, I don’t know if I need to align these sequence with existing antibody sequence first when screening antibodies, and then use sequences with a higher identity for antibody modeling?
I would appreciate it very much if you would help me with it.