The Yeast Metabolic Engineering group develops novel yeast cell factories for the production of sustainable chemicals and natural products. We apply advanced genome editing, metabolic modeling, and ‘omic data analyses for data-guided strain design. We are looking for a motivated and talented researcher to join our team.
The position is within expression and characterization of transport proteins for small metabolites.
Responsibilities and tasks
You will develop methods for expression of membrane proteins and for characterization of transport protein activity using solid-supported membrane-based electrophysiology (SURFE2R system from Nanion Technologies). In collaboration with other team members, you will apply the knowledge to create and improve yeast cell factories.
- Development of innovative approaches to produce membrane proteins
- Characterization of membrane protein activity using SURFE2R system and other methods
- Experimental design, hands-on data acquisition and analysis
- Reporting results in peer-reviewed publications and presentations at conferences and meetings
- Collaboration within the group and within DTU Biosustain, participation in international collaborations
Candidates should have a PhD degree or equivalent.
- Hands-on experience with membrane protein expression. Experience with cell-free protein expression is a plus
- Previous experience with transport protein research is desirable
- Experience with Xenopus expression system is a benefit
- Excellent track-record of scientific achievements (publications, patents, awards, grants, conference presentations, etc.)
- Ability to work independently, to plan and carry out complicated research tasks, and also to be a part of the large research team
- Experience in project planning and supervision of students or laboratory technicians
- Team spirit and excellent collaboration skills
- Strong analytical skills and excellent judgment ability
- Excellent communication skills, fluent written and oral English
- Well-organized, efficient, result-oriented, have excellent record keeping abilities.
DTU is a leading technical university globally recognized for the excellence of its research, education, innovation and scientific advice. We offer a rewarding and challenging job in an international environment. We strive for academic excellence in an environment characterized by collegial respect and academic freedom tempered by responsibility.
Salary and terms of employment
The appointment will be based on the collective agreement with the Danish Confederation of Professional Associations. The allowance will be agreed upon with the relevant union.
The period of employment is 2 years.
You can read more about career paths at DTU here.
Further information may be obtained from Prof. Irina Borodina, tel.: +45 21 79 86 57.
You can read more about “the Department” at www.biosustain.dtu.dk
Please submit your online application no later than 30 September 2020.
Apply online at www.career.dtu.dk.
Applications must be submitted as one PDF file containing all materials to be given consideration. To apply, please open the link "Apply online", fill out the online application form, and attach all your materials in English in one PDF file. The file must include: - Application (cover letter) - CV - Diploma (PhD) - List of publications
Applications and enclosures received after the deadline will not be considered.
All interested candidates irrespective of age, gender, disability, race, religion or ethnic background are encouraged to apply.
*The Novo Nordisk Foundation Center for Biosustainability (DTU Biosustain)
Recent progress in our ability to read and write genomic code, combined with advances in automation, analytics and data science, has fundamentally changed the scope and ambition of harnessing the potential of biological systems. Big data approaches and analysis of biological systems are key research instruments at the Center. DTU Biosustain utilizes these advances for microbial cell factory design to foster sustainable lifestyles in relation to three application areas: Sustainable Chemicals, Natural Products, and Microbial Foods.
Technology for people
DTU develops technology for people. With our international elite research and study programmes, we are helping to create a better world and to solve the global challenges formulated in the UN’s 17 Sustainable Development Goals. Hans Christian Ørsted founded DTU in 1829 with a clear vision to develop and create value using science and engineering to benefit society. That vision lives on today. DTU has 12,000 students and 6,000 employees. We work in an international atmosphere and have an inclusive, evolving, and informal working environment. Our main campus is in Kgs. Lyngby north of Copenhagen and we have campuses in Roskilde and Ballerup and in Sisimiut in Greenland.*