Question: How to classify Tumor Mutation Burden into TMB high, medium and low groups ?
1
gravatar for svp
4 months ago by
svp420
Bangalore
svp420 wrote:

Tumor mutational burden (TMB) is a measure of the number of gene mutations inside the cancer cells. TMB of a tumor sample is calculated by the number of non-synonymous somatic mutations per mega-base in coding regions. The value obtained for TMB always ranges from 0 to 1 which never reaches 1. What is the minimal cut-off that can be assigned to classify TMB as High, Medium and Low?

ADD COMMENTlink modified 4 months ago by Karma300 • written 4 months ago by svp420
1
gravatar for Karma
4 months ago by
Karma300
India
Karma300 wrote:

There is specified cut-off for stratifying the tumor mutation burden.

You can go through these papers p1, p2, p3

ADD COMMENTlink written 4 months ago by Karma300
Please log in to add an answer.

Help
Access

Use of this site constitutes acceptance of our User Agreement and Privacy Policy.
Powered by Biostar version 2.3.0
Traffic: 1752 users visited in the last hour
_