Question: How to classify Tumor Mutation Burden into TMB high, medium and low groups ?
gravatar for svp
4 months ago by
svp420 wrote:

Tumor mutational burden (TMB) is a measure of the number of gene mutations inside the cancer cells. TMB of a tumor sample is calculated by the number of non-synonymous somatic mutations per mega-base in coding regions. The value obtained for TMB always ranges from 0 to 1 which never reaches 1. What is the minimal cut-off that can be assigned to classify TMB as High, Medium and Low?

ADD COMMENTlink modified 4 months ago by Karma300 • written 4 months ago by svp420
gravatar for Karma
4 months ago by
Karma300 wrote:

There is specified cut-off for stratifying the tumor mutation burden.

You can go through these papers p1, p2, p3

ADD COMMENTlink written 4 months ago by Karma300
Please log in to add an answer.


Use of this site constitutes acceptance of our User Agreement and Privacy Policy.
Powered by Biostar version 2.3.0
Traffic: 1752 users visited in the last hour