How does your sequencing center communicate the relationship between samples, flowcells/lanes (or other sequencer setups), and barcodes. Given the many-to-many schemes that people cook up this seems like a huge source of error.
Is there a data format and/or LIMS that a technician can easily use for this purpose?
Something that drives me nuts is a lack of documentation coming from collaborators. I know it's not meta data, but at least you could tell me: did you trim the reads? what is the platform? who should I send correspondence to? A hard drive containing unknown fastqs is a daily nightmare.